Coley, HM; Safuwan, NA; Chivers, P; Papacharalbous, E; Giannopoulos, T; Butler-Manuel, S; Madhuri, K; Lovell, DP; Crook, T
(2012)
The cyclin-dependent kinase inhibitor p57(Kip2) is epigenetically regulated in carboplatin resistance and results in collateral sensitivity to the CDK inhibitor seliciclib in ovarian cancer.
BRITISH JOURNAL OF CANCER, 106 (3).
482 - 489 (8).
ISSN 0007-0920
https://doi.org/10.1038/bjc.2011.566
SGUL Authors: Lovell, David
| Item Type: |
Article
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| Additional Information: |
PubMed ID: 22233925 |
| Keywords: |
Antineoplastic Agents, Carboplatin, Cell Line, Tumor, Cyclin-Dependent Kinase Inhibitor p27, DNA Methylation, Dose-Response Relationship, Drug, Down-Regulation, Drug Resistance, Neoplasm, Epigenesis, Genetic, Female, Humans, Ovarian Neoplasms, Purines, Science & Technology, Life Sciences & Biomedicine, Oncology, ovarian cancer, p57(Kip2), epigenetically silenced, carboplatin resistance, seliciclib, EXPRESSION, METHYLATION, P27(KIP1), SURVIVAL, AGENTS, CELLS, GENE, P53, D1, ovarian cancer, p57(Kip2), epigenetically silenced, carboplatin resistance, seliciclib |
| SGUL Research Institute / Research Centre: |
Academic Structure > Institute of Medical & Biomedical Education (IMBE)
Academic Structure > Institute of Medical & Biomedical Education (IMBE) > Centre for Biomedical Education (INMEBE) |
| Journal or Publication Title: |
BRITISH JOURNAL OF CANCER |
| ISSN: |
0007-0920 |
| Dates: |
| Date | Event |
|---|
| 31 January 2012 | Published |
|
| Web of Science ID: |
WOS:000300302300009 |
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| URI: |
http://sgultest.da.ulcc.ac.uk/id/eprint/101427 |
| Publisher's version: |
https://doi.org/10.1038/bjc.2011.566 |
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